青岛大学医学院学报2017，Vol.53Issue(3)：291-293,3.DOI:10.13361/j.qdyxy.201703011
颅骨缺损后不同时间修补术对病人脑血流动力学影响
INFLUENCE OF CRANIOPLASTY PERFORMED AT DIFFERENT TIME POINTS AFTER CRANIAL DEFECT ON CEREBRAL HEMODYNAMICS
白亚强 1邵永祥 1彭华1
作者信息
- 1. 宜宾市第二人民医院神经外二科,四川宜宾 644000
- 折叠
摘要
Abstract
Objective To investigate the influence of cranioplasty performed at different time points after cranial defect on cerebral hemodynamics.Methods A total of 62 patients who planned to undergo unilateral cranial defect repair were divided into early-repair group (within 12 weeks after cranial defect) and late-repair group (≥12 weeks after cranial defect),with 31 patients in each group.256-slice spiral CT for cerebral perfusion scan was performed within 5 days before repair and within 12 days after repair to record the values of regional cerebral blood volume (rCBV),regional cerebral blood flow (rCBF),mean transit time (MTT) of contrast agent,and time to peak (TTP) of contrast agent on the perfusion images of the affected cerebral cortex,basal ganglia,and thalamus.The changes in rCBV,rCBF,MTT,and TTP after surgery were analyzed in both groups.Results Compared with the late-repair group,the early-repair group had significantly greater changes in rCBF in the affected cerebral cortex and basal ganglia (t=5.32,7.26;P＜0.05) and MTT in the basal ganglia after surgery (t=10.73,P＜0.05).Conclusion Early cranioplasty helps to improve cerebral hemodynamics and cerebral perfusion in patients with cranial defect.关键词
颅骨/再手术/脑血流动力学/灌注成像Key words
skull/reoperation/hemodynamics/perfusion imaging分类
医药卫生引用本文复制引用
白亚强,邵永祥,彭华..颅骨缺损后不同时间修补术对病人脑血流动力学影响[J].青岛大学医学院学报,2017,53(3):291-293,3.
