血清脂蛋白相关磷脂酶A2和胱抑素C联合检测对SLE患者并发狼疮性肾炎的风险评估OA
Risk Assessment of Combined Detection of Lipoprotein Associated Phospholipase A2 and Cystatin C for Lupus Nephritis in Patients with Systemic Lupus Erythematosus
目的 探讨血清脂蛋白相关磷脂酶A2(LP-PLA2)与胱抑素C(CysC)联合检测在系统性红斑狼疮(SLE)患者中并发狼疮性肾炎的应用价值.方法 收集2016年6月～2017年2月在解放军总医院住院的SLE患者177例,其中肾脏不受累的患者87例,狼疮性肾炎(LN)患者90例,收集年龄性别匹配的健康查体人员60例,分别记为狼疮组(SLE组)、狼疮性肾炎组(LN组)和对照组.检测各组标本LP-PLA2的活性水平和CysC浓度,做ROC曲线确立SLE…查看全部>>
Objective To investigate the value of combinedevaluation of serum lipoprotein associated phospholipase A2 (LP-PLA2) and cystatin C (CysC) on systemic lupus erythematosus (SLE) patients with lupus erythematosus.Methods A total of 177 patients with SLE were enrolled in the General Hospital of People's Liberation Army from June 2000 to February 2017,87 cases in lupus group (SLE group),90 cases in lupus nephritis group (LN group),60 cases in healthy control grou…查看全部>>
王坤;贾兴旺;董矜;颜光涛
解放军总医院生化科,北京 100853解放军总医院生化科,北京 100853解放军总医院生化科,北京 100853解放军总医院生化科,北京 100853
医药卫生
脂蛋白相关磷脂酶A2胱抑素C系统性红斑狼疮狼疮性肾炎
lipoprotein-related phospholipase A2cystatin Csystemic lupus erythematosuslupus nephritis
《现代检验医学杂志》 2017 (4)
6-8,11,4
国家科技支撑计划(2015BAK45B01).
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