天然产物研究与开发2017，Vol.29Issue(7)：1136-1140,5.DOI:10.16333/j.1001-6880.2017.7.010
海洋来源真菌Aspergillus sp.SCSIO 41501中含氮化合物
N-containing Compounds of Marine-derived Fungus Aspergillus sp.SCSIO 41501
摘要
Abstract
Eleven N-containing compounds were isolated from a culture broth of the fungal strainAspergillus sp.SCSIO 41501 isolated from the China South Sea gorgonian Melitodessquamata.They were identified as13-(S)-ochratoxin A (1),13-(S)-ochratoxin A methyl ester (2),13-(R)-ochratoxin A (3),4-(R)-OH-ochratoxin A (4),18-OH-ochratox-in A (5),transtorine (6),quinolactacin C1 (7),marinamide (8),methyl Marinamide (9),aspergilliamide (10),and anoectochine(11) on the basis of spectroscopic analyses (1 D NMR and ESI-MS) and by comparison of the NMR data with literatures.All the compounds were tested for their antibacterial activity.Compounds2and 3showed moderateantibacterial activity against Escherichia coli,Bacillus subtilis and Staphylococcus aureus with MIC values of 31.25,7.8,15.6μg/mL for 2,and 62.5,31.25,62.5 μg/mL for 3,respectively.关键词
海洋真菌/Aspergillus sp.SCSIO 41501/含氮化合物Key words
marine fungus/Aspergillus sp.SCSIO 41501/secondary metabolism分类
医药卫生引用本文复制引用
马宣,农旭华,黄钟辉,梁潇,王洁,漆淑华..海洋来源真菌Aspergillus sp.SCSIO 41501中含氮化合物[J].天然产物研究与开发,2017,29(7):1136-1140,5.基金项目
国家自然科学基金(41376160 （）
81673326) （）
