安徽农业科学2017，Vol.45Issue(24)：137-139,3.
DNA N6-甲基腺嘌呤(6mA)在真核生物中的研究进展
Research Progress of DNA N6-methyladenine (6mA) in Eukaryotes
摘要
Abstract
Methylation at cytosine of DNA has long been considered as the only modified bases in vertebrate, until the methylation at adenine site was discovered in recent studies.6mA is a newly studied base in higher eukaryotes, this modification is in a wide prevalence and conserved among eukaryotic species.The level of 6mA is dynamically changing and it plays important biological functions in the whole life cycle.This paper was mainly to review researches of 6mA in recent years, explore its conservatism in evolution and the biological function in eukaryotes, elucidate the mechanism of enzymes, then sum up the common used methods in recent studies of detecting 6mA.Finally, put forward the prospect of 6mA research in the future.关键词
N6-甲基腺嘌呤(6mA)/表观遗传学/生物学功能/甲基转移酶/去甲基酶Key words
N6-methyladenine/Epigenetics/Biological function/Methyltransferase/Demethylase分类
农业科技引用本文复制引用
李锋..DNA N6-甲基腺嘌呤(6mA)在真核生物中的研究进展[J].安徽农业科学,2017,45(24):137-139,3.基金项目
西华师范大学2017年度基本科研业务费项目——青年教师资助项目(17D079). （17D079）
