中国耳鼻咽喉头颈外科2017，Vol.24Issue(7)：329-332,4.DOI:10.16066/j.1672-7002.2017.07.001
cN0甲状腺乳头状癌患者颈淋巴结转移的高危因素分析
Analysis on risk factors of cervical lymph node metastasis in cN0 papillary thyroid carcinom
庞玉娟 1陈晓红 2张景义 1高景利1
作者信息
- 1. 华北理工大学附属医院开滦总医院内分泌科,河北 唐山 063000
- 2. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,耳鼻咽喉头颈科学教育部重点实验室(首都医科大学),北京 100730
- 折叠
摘要
Abstract
OBJECTIVE To explore risk factors of cervical lymph node metastasis in cN0 papillary thyroid carcinoma. METHODS The clinical data of 537 patients with cN0 papillary thyroid carcinoma were analyzed retrospectively in Beijing Tongren hospital from Jan 2009 to Dec 2015. Patients' gender, age, multifocal lesion, carcinoma complicated with Hashimoto's thyroiditis, capsule breakthrough and tumor size were counted. RESULTS The lymph node metastasis rate of 537 patients with cN0 papillary thyroid carcinoma was 30.9%(166/537). The incidences of lymph node involvement were 24.95%(166/537) at only level VI, 5.21%(28/537) at level VI plus lateral part of neck and 0.74%(4/537) at only skip metastasis, respectively. Chi square test and multivariate logistic regression analysis showed that cervical lymph node metastasis was statistically associated with male, age<45 years, capsule breakthrough and tumor diameter>1 cm (P<0.05). After the operation, there were 17 patients with temporary hoarseness, accompanied with 1 loss to follow-up and 1 failure to return to normal after 1.5 years. There were 61 patients with temporary hypocalcemia, 2 patients failed to follow-up and 2 patients with calcium supplements after respective 1.5 and 4 years. CONCLUSION To stratify the risk of patients with cN0 papillary thyroid carcinoma, male, age<45 years, capsule breakthrough and tumor diameter>1 cm are risk factors for cervical lymph node metastasis. And we suggest that prophylactic central lymph node dissection may be appropriate.关键词
甲状腺肿瘤/肿瘤,乳头状/危险因素/淋巴结转移/颈Key words
Thyroid Neoplasms/Adenocarcinoma/Papillary/Risk Factors/Lymph Node/Neck引用本文复制引用
庞玉娟,陈晓红,张景义,高景利..cN0甲状腺乳头状癌患者颈淋巴结转移的高危因素分析[J].中国耳鼻咽喉头颈外科,2017,24(7):329-332,4.
