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不同剂型硝磺草酮及其原药对斑马鱼的急性毒性评价

宋世明 陈兆杰 吴秋榕 李远富 邓程 赖开平 谭辉华 李雪生

南方农业学报2017,Vol.48Issue(8):1518-1523,6.
南方农业学报2017,Vol.48Issue(8):1518-1523,6.DOI:10.3969/j.issn.2095-1191.2017.08.30

不同剂型硝磺草酮及其原药对斑马鱼的急性毒性评价

Acute toxicity of mesotrione in different formulation and technical materials to zebrafish

宋世明 1陈兆杰 1吴秋榕 1李远富 1邓程 1赖开平 2谭辉华 1李雪生1

作者信息

  • 1. 广西大学 农药与环境毒理研究所/广西农业环境与农产品安全重点实验室培育基地,南宁 530004
  • 2. 广西化工研究院,南宁 530001
  • 折叠

摘要

Abstract

[Objective]The aim of the present study was to evaluate the acute toxicity of mesotrione in different for-mulations and technical materials to zebrafish,provide basic data for environmental ecological risk assessment for mesot-rione. At the same time,it could provide reference for rational use of this pesticide.[Method]Acute toxicity of mesotrione in different formulations and technical materials to zebrafish was evaluated using static test. Toxicity levels of median lethal concentrationto zebrafish in 96 h(96 h-LC50)for the tested pesticides were divided based on Experimental Guideline for Environmental Safety Evaluation of Chemical Pesticides(GB/T 31270.12-2014).[Result]Under the same exposure time,LC50 of mesotrione in different formulations and technical materials to zebrafish was different. 96 h-LC50(95%confi-dence limit)of 10%mesotrione oil dispersion(OD)was the lowest[6.70(5.18~8.15)mg a.i./L],followed by 10%mesot-rione suspension concentrate(SC),and 75%mesotrione water dispersible granule(WDG)which were 10.89(9.29-12.43) and 38.97(30.83-47.51)mg a.i./L respectively. 96 h-LC50 of 98%mesotrione technical material(TM)to zebrafish was the largest,more than 1.00 × 102 mg a. i./L. According to the Experimental Guideline for Environmental Safety Evaluation of Chemical Pesticides(GB/T 31270.12-2014),the toxicity of 10% mesotrione SC to zebrafish was moderate,while the others were low. The rank of toxicity was:10% mesotrione SC>10% mesotrione OD>75% mesotrione WDG>98%mesotrione TM.[Conclusion]Acute toxicity of mesotrione in different formulations and technical materials to zebrafish is different,the rank is as follows:mesotrione SC>mesotrione OD>mesotrione WDG>mesotrione TM. Therefore,in field cultivation,the formulations of pesticide should be selected accordingly,and the application dosage should be controlled to reduce the negative influence on fish caused by pesticides entering water area environment.

关键词

斑马鱼/硝磺草酮/剂型/原药/急性毒性

Key words

zebrafish/mesotrione/formulation/technical material/acute toxicity

分类

农业科技

引用本文复制引用

宋世明,陈兆杰,吴秋榕,李远富,邓程,赖开平,谭辉华,李雪生..不同剂型硝磺草酮及其原药对斑马鱼的急性毒性评价[J].南方农业学报,2017,48(8):1518-1523,6.

基金项目

国家重点研发计划项目(2016YFD0201208-4) (2016YFD0201208-4)

广西重点实验室培育基地建设项目(桂科基字[2016]133号) (桂科基字[2016]133号)

南方农业学报

OA北大核心CSCDCSTPCD

2095-1191

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