海南医学院学报2017,Vol.23Issue(15):2025-2028,4.DOI:10.13210/j.cnki.jhmu.20170810.014
有氧运动训练对老年冠心病伴慢性心力衰竭患者红细胞参数、血管内皮功能的影响
Effect of aerobic exercise training on red blood cell parameters, vascular endothelial function in elderly patients with coronary heart disease and chronic heart failure
摘要
Abstract
Objective: To investigate the effect of aerobic exercise training combined with routine medication on the red blood cell parameters, vascular endothelial function and cardiac function in elderly patients with coronary heart disease complicated with chronic heart failure.Methods: A total of 110 elderly patients with coronary heart disease and chronic heart failure were divided into control group (n=54) and observation group (n=56) according to random data table.The patients in control group were treated with routine medicine, and the patients in the observation group received routine medicine combined with aerobic exercise training.The levels of the red blood cell parameters, vascular endothelial function and cardiac function indexes before and after treatment were compared between the two groups.Results: Before treatment, there was no significant difference in HCT, RDW, RBC, NO, ET-1, LVEF, LVEDD and LVESD levels between the two groups (P>0.05).After treatment, the differences in HCT and RBC levels between two groups were not statistically significant (P>0.05);The levels of RDW, ET-1, LVEDD and LVESD in the observation group after treatment were significantly lower than that before treatment, and significantly lower than that of the control group after treatment (P<0.05);The levels of NO and LVEF in the two groups after treatment were significantly higher than that before treatment (P<0.05), and the levels of NO and LVEF in the observation group were significantly higher than that of the control group after treatment (P<0.05).Conclusion: The clinical effect of aerobic exercise training combined with routine medication in the treatment of senile coronary heart disease accompanied by chronic heart failure was significant, which can effectively improve vascular endothelial function and heart function, and increase the RDW level of patients, it has important clinical value.关键词
冠心病伴慢性心力衰竭/有氧运动/红细胞参数/血管内皮功能/心功能Key words
Coronary heart disease with chronic heart failure/Aerobic exercise training/Red blood cell parameter/Vascular endothelial function/Cardiac function分类
医药卫生引用本文复制引用
马庆平,郇赛,顾莹,刘敏,孟莹..有氧运动训练对老年冠心病伴慢性心力衰竭患者红细胞参数、血管内皮功能的影响[J].海南医学院学报,2017,23(15):2025-2028,4.基金项目
山东省科技攻关项目(2013GG12345128)This study was supported by Scientific and Technological project in Shandong Province (2013GG12345128). (2013GG12345128)