河北医学2017，Vol.23Issue(8)：1310-1316,7.DOI:10.3969/j.issn.1006-6233.2017.08.022
N-末端脑钠肽前体对冠状动脉旁路移植术术后房颤的预测价值
Predictive Value of N-terminal Brain Natriuretic Peptide Precursor for Atrial Fibrillation after Coronary Artery Bypass Grafting
摘要
Abstract
Objective:To investigate the diagnostic value of N-terminal brain natriuretic peptide(BNP)in patients with atrial fibrillation after coronary artery bypass grafting(CABG).Methods: 132 cases in our hospital underwent coronary artery bypass grafting were selected in September 2011 to January 2015 were the observation of outcomes were atrial fibrillation events after operation,39 cases divided into AF group and 93 cases into sinus rhythm group,the basic data of all patients were collected,including age BMI,EuroScore,NYHA,gender,grade,basic diseases(hypertension,diabetes),oral drugs(beta blockers,calcium channel blockers,statins),intensive care time,ventilator time,record cardiac ultrasound(LAD,LVESD,IVST,LVEDD,LVEF(NT-proBNP)and biochemical examination ALT,AST,hs-CRP,Cr,RBC,RDW),the dependent variable of postoperative atrial fibrillation,using single factor analysis of the difference between indicators as independent variables,multivariate regression analysis for Logistic.Results: The incidence of postoperative atrial fibrillation was 29.55％(39/132),the incidence of atrial fibrillation in CCABG group(46.94％)was higher than that of OPCAB group(19.28％),there are differences(P<0.05).AF group and sinus rhythm group in average age,EuroScore,NYHA grade,intensive care time,ventilator time,beta receptor antagonist,difference(P<0.05).AF group and sinus rhythm group in postoperative 24h LAD,after 24h LVEF,there are differences(P<0.05).AF group and sinus rhythm group at NT-proBNP,24h after surgery and postoperative 24h hs-CRP RDW,there are differences(P<0.05).age,postoperative 24h LAD,NT-proBNP after surgery as an independent predictor of coronary artery bypass grafting with atrial fibrillation(P<0.05).Conclusion: Age,postoperative 24h,LAD,and NT-proBNP were independent predictors of atrial fibrillation after coronary artery bypass grafting.关键词
N-末端脑钠肽前体/冠状动脉旁路移植术/术后房颤/诊断价值Key words
N-terminal pro brain natriuretic peptide/Coronary artery bypass grafting/Postoperative atrial fibrillation/Diagnostic value引用本文复制引用
王兆东,周保国,马骏,梁雁翎,魏勇,迟增鑫,胡瑞成,张振宇..N-末端脑钠肽前体对冠状动脉旁路移植术术后房颤的预测价值[J].河北医学,2017,23(8):1310-1316,7.基金项目
山东省卫生厅科研计划项目,(编号:2013WS2761) （编号:2013WS2761）
