核农学报2017，Vol.31Issue(10)：1993-1997,5.DOI:10.11869/j.issn.100-8551.2017.10.1993
刺苋花粉过敏性评价研究
Evaluation of Amaranthus Spinosus Pollen Allergy
摘要
Abstract
Amaranthus spinosus L.is a kind of invasive plants,thorn amaranth pollen has become an important allergen in south China,and the Amaranthus spinosus L.pollen allergen easily with other cross-reactive allergens.To investigate the hypersensitivity,Amaranthus spinosus L.Pollen,allergen,the BALB /c mice were intraperitoneally injected with,sensitive nose drops stimulate the establishment of BALB /c mice allergy evaluation model.Through the on the nasal symptoms were observed and score,nasal secretion smear staining were observed and serum histamine and IgE content determination,and the anatomy of mouse lung were observed by HE staining to identify mouse induced by sensitizing dose.The results revealed that the content of IgE increased linearly with the increase of injection quantity,the content of IgE reached a maximum when the injection dose is 75 μg,the content of histamine also increased linearly with the increase of injection of low doses,and after the injection of doses reached 38 μg,the content of histamine changed slowly,75 μg injection doses can cause the serious anaphylactic reaction and inflammatory to lung infection.Amaranthus spinosus L.pollen allergy evaluation study provides a supplement to a comprehensive health risk assessment of invasive plants.关键词
刺苋花粉/超声提取/动物模型/BALB/c小鼠/H&E染色Key words
Amaranthus spinosus L.Pollen/ultrasonic extraction/animal model/BALB/c mice/H&E staining引用本文复制引用
林敏,张媚,潘家荣,高原,傅丽丽,李树磊,金俊,冯涛..刺苋花粉过敏性评价研究[J].核农学报,2017,31(10):1993-1997,5.基金项目
质检类公益项目(201410014-5) （201410014-5）
