河南中医2017，Vol.37Issue(8)：1389-1391,3.DOI:10.16367/j.issn.1003-5028.2017.08.0488
足三里穴位埋线法对阿德福韦酯应答不佳慢性乙型病毒性肝炎患者的影响
The Influence of Acupoint Catgut Embedding in Zusanli on Patients with Chronic Hepatitis B and Poor Response to Adefovir Dipivoxil
沈瑞南 1杨爱水 1吴昊鹤 1周东红 1陈延光1
作者信息
摘要
Abstract
Objective:To observe the influence of acupoint catgut embedding in Zusanli (ST 36) on patients with chronic hepatitis B and poor response to adefovir dipivoxil.Methods:One hundred patients who met the inclusion criteria were randomly divided into the treatment group and the control group,with 50 eases in each group.All the patients were given Adefovir Dipivoxil Capsules in the early treatment stage.Before the treatment and after 24 weeks' treatment,all the patients' HBV-DNA ration,HBeAg ration and complement C3 were measured respectively.The patients who were treated for 24 weeks with HBV-DNA ration ＞ 5 × 102 IU · mL-1(poor response) were regarded as the research objects.The control group was treated with the original treatment regimen.The treatment group was treated with Catgut Implantation at the bilateral Zusanli (ST 36) on the basis of the original treatment regimen.After 24 weeks,the HBV-DNA,HBeAg and complement C3 in the two groups were measured respectively.Results:After 24 weeks of conventional treatment,the differences in the negative rate of HBV-DNA and HBeAg rate in the two groups were not statistically significant (P ＞ 0.05).After 24 weeks of treatment,the complement C3 of the two groups was higher than that before treatment,but there was no statistical difference between the two groups (P ＞ 0.05).After 48 weeks's treatment,the negative rate sof HBV-DNA and HBeAg and the complement C3 of the treatment group were lower than those of the control gToup,and the differences were statistically significant (P ＜ 0.05).Conclusion:For the poor response to Adefovir Dipivoxil Capsules in patients with chronic hepatitis B,Zusanli (ST 36) catgut embedding therapy can significantly improve the negative rates of HBV-DNA,HBeAg and complement C3,can significantly shorten the course of treatment of patients,and improve the clinical efficacy.关键词
慢性乙型病毒性肝炎/足三里/穴位埋线/阿德福韦酯/补体C3/HBeAg转阴率/HBV-DNA转阴率Key words
chronic hepatitis B/Zusanli (ST 36)/acupoint catgut embedding/adefovir dipivoxil/complement C3/HBeAg negative rate/HBV-DNA negative rate分类
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沈瑞南,杨爱水,吴昊鹤,周东红,陈延光..足三里穴位埋线法对阿德福韦酯应答不佳慢性乙型病毒性肝炎患者的影响[J].河南中医,2017,37(8):1389-1391,3.
