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人诱导性多潜能干细胞建立心肌细胞疾病模型的研究进展

崔宁 李蕾 崔鸣 兰峰

基础医学与临床2017,Vol.37Issue(9):1331-1335,5.
基础医学与临床2017,Vol.37Issue(9):1331-1335,5.

人诱导性多潜能干细胞建立心肌细胞疾病模型的研究进展

Research progress of establishing cardiomyocytedisease models by human induced pluripotent stem cells

崔宁 1李蕾 1崔鸣 1兰峰2

作者信息

  • 1. 北京大学第三医院 心内科,北京 100191
  • 2. 首都医科大学附属北京安贞医院 北京市心肺血管疾病研究所,北京 100029
  • 折叠

摘要

Abstract

Induced pluripotent stem cell is a landmark in the stem cell study field, which has rapidly developed in the past 10 years.By obtaining induced pluripotent stem cells from somatic cell, and then differentiating into cardiomyocyte, various cardiomyocyte disease models could be established,which can be used for research of disease mechanisms, drug screening and gene therapy.This review introduces the successfully established cardiomyocyte disease models from human induced pluripotent stem cells, and points out the problems and prospects.

关键词

诱导性多潜能干细胞/心肌细胞疾病模型/研究进展

Key words

induced pluripotent stem cell/cardiomyocyte disease model/research progress

分类

生物科学

引用本文复制引用

崔宁,李蕾,崔鸣,兰峰..人诱导性多潜能干细胞建立心肌细胞疾病模型的研究进展[J].基础医学与临床,2017,37(9):1331-1335,5.

基础医学与临床

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1001-6325

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