解放军医学院学报2017，Vol.38Issue(8)：741-744,4.DOI:10.3969/j.issn.2095-5227.2017.08.009
宝石能谱CT检测不同痛风患者足踝关节尿酸盐沉积的临床价值
Diagnostic value of uric acid quantification in feet and ankles in gout patients using gemstone spectral imaging computerized tomography technology
摘要
Abstract
Objective To investigate the diagnostic value of gemstone spectral imaging (GSI) CT technology in detecting uric acid quantification in gout patients' feet and ankles.Methods From August 2013 to April 2016,a total of 89 patients in the department of rheumatology in Hainan Branch of Chinese PLA General Hospital were enrolled in this study and underwent CT scans with GSI mode.These patients were divided into three groups:35 gout patients with clinically detectable tophus in group A,36 patients with asymptomatic hyperuricemia in group B,and 18 patients with other arthropathies in group C as controls.Two locations including soft tissues beside bilateral first metatarsophalangeal joints (FMTPJs) and bilateral exteral malleoli were selected for quantitative analysis of uric acid and hydroxyapatite (HAP).Results There were significant differences in uric acid (HAP) concentration of three groups in soft tissues beside FMTPJs [A:(1186.32 ± 23.86) mg/cm3 ＞ B:(1157.71 ± 19.35) mg/cm3 ＞ C:(1123.62 ± 10.51) mg/cm3,P ＜0.05] and sofi tissues beside malleoli [A:(1162.71 ± 30.12) mg/cm3 ＜ B:(1139.32 ± 11.57) mg/cm3 ＜ C:(1123.0 ± 9.07) mg/cm3,P ＜ 0.05],respectively.Conclusion The uric acid deposits in feet and ankles of patients with tophaceous gout is more serious than that in the same locations of those patients with hyperuricemia examined by GSI-CT technology.关键词
宝石能谱CT/痛风/高尿酸血症Key words
gemstone spectral imaging CT/gout/hyperuricemia分类
医药卫生引用本文复制引用
李白鸽,梁东风,邢宁,邓小虎,朱剑,张晓欢..宝石能谱CT检测不同痛风患者足踝关节尿酸盐沉积的临床价值[J].解放军医学院学报,2017,38(8):741-744,4.基金项目
海南省自然科学基金项目(814332)Supported by the Natural Science Foundation of Hainan Province(814332) （814332）
