临床肝胆病杂志2017，Vol.33Issue(8)：1584-1588,5.DOI:10.3969/j.issn.1001-5256.2017.08.038
神经酰胺在非酒精性脂肪性肝病发生发展中的作用
Role of ceramide in development and progression of nonalcoholic fatty liver disease
摘要
Abstract
Nonalcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome caused by liver damage factors except alcohol and has the major feature of diffuse macrovesicular hepatocyte steatosis.The " two-hit" hypothesis can partly explain the pathogenesis of NAFLD.Recent studies have found that ceramide is a key molecular messenger involved in the development and progression of NAFLD,and as a sphingolipid,it is closely associated with the "two-hit" hypothesis.This article reviews the role of ceramide in NAFLD.关键词
脂肪肝/神经酰胺类/综述Key words
fatty liver/ceramides/review分类
医药卫生引用本文复制引用
韩海静,齐雪,牛春燕..神经酰胺在非酒精性脂肪性肝病发生发展中的作用[J].临床肝胆病杂志,2017,33(8):1584-1588,5.基金项目
陕西省优势学科(陕教位[2014]3号文件) （陕教位[2014]3号文件）
