临床神经病学杂志2017，Vol.30Issue(4)：303-305,3.
早期静脉溶栓治疗急性轻型缺血性卒中的疗效观察
Observation of curative effect of early intravenous thrombolysis treatment on acute minor ischemic stroke
摘要
Abstract
Objective To evaluate the efficacy and safety early intravenous thrombolysis treatment on acute minor ischemic stroke.Methods Seventy patients with first-acute mild ischemic stroke were randomly divided into thrombolysis group (35 cases) and non-thrombolysis group (35 cases).Thrombolysis group was received intravenous thrombolysis treatment with recombinant tissue plasminogen activator (rt-PA) at admission, non-thrombolysis group was taken aspirin (100 mg/d) orally.Neurological deficit situation was evaluated by NIHSS at discharge, and the clinical outcome were evaluated by modified Rankin scale (mRS) at 3 months after treatment.Results There was no significant difference of baseline clinical data at admission between thrombolysis group and non-thrombolysis group (all P>0.05).Compared with non-thrombolysis group, NIHSS score in thrombolysis group at discharge was significantly decreased, and the rate of good prognosis in thrombolysis group at 3 month was significantly increased (P<0.05-0.01).There was no symptomatic intracerebral hemorrhage and died in the two groups.Conclusion Early intravenous thrombolysis treatment can improve the prognosis of acute minor ischemic stroke, and the risk of symptomatic intracerebral hemorrhage would not increase.关键词
急性轻型缺血性脑卒中/静脉溶栓治疗/重组组织型纤溶酶原激活剂/预后Key words
acute minor ischemic stroke/intravenous thrombolysis treatment/recombinant tissue plasminogen activator/prognosis分类
医药卫生引用本文复制引用
杨江胜,朱祖福,高志强,张慧萍,陆强彬,方琪..早期静脉溶栓治疗急性轻型缺血性卒中的疗效观察[J].临床神经病学杂志,2017,30(4):303-305,3.基金项目
无锡市卫生局面上项目(MS201409) （MS201409）
