同济大学学报（医学版）2017，Vol.38Issue(4)：37-40,4.DOI:10.16118/j.1008-0392.2017.04.008
组织芯片技术检测SFRP4在人胰腺癌组织中的表达
Expression of SFRP4 in pancreatic cancer detected by tissue microarray
摘要
Abstract
Objective To detect the expression of SFRP4 in pancreatic cancer by tissue microarray.Methods The expression of SFRP4 protein in 90 pancreatic cancer specimens was detected by immunohistochemistry on tissue microarrays.Results SFRP4 protein was mainly expressed in the cytoplasm of cells.The positive expression rate of SFRP4 in pancreatic cancer tissue was higher than that in the tissue adjacent to carcinoma (31.1% vs 14.4%,P<0.05).The expression of SFRP4 was not correlated with the age,sex,tumor size,AJCC-TNM stages and prognosis of patients (P>0.05).Conclusion The expression of SFRP4 is up-regulated in pancreatic cancer,indicating that it may be associated with the carcinogenesis of pancreatic cancer.关键词
SFRP4/胰腺肿瘤/组织芯片Key words
SFRP4/pancreatic cancer/tissue microarray分类
医药卫生引用本文复制引用
姚倩,李青青,江华..组织芯片技术检测SFRP4在人胰腺癌组织中的表达[J].同济大学学报（医学版）,2017,38(4):37-40,4.基金项目
上海市浦东新区卫生系统领先人才培养计划(PWR12012-01) （PWR12012-01）
