世界中医药2017，Vol.12Issue(7)：1569-1572,4.DOI:10.3969/j.issn.1673-7202.2017.07.022
金匮肾气丸辅助治疗对支气管哮喘缓解期患者免疫功能的影响
Influence of Jinkuishenqiwan Adjuvant Therapy on Immune Function in Adult Bronchial Asthma in Remission Stage Patients
摘要
Abstract
Objective:To study the influence of Jinkuishenqiwan adjuvant therapy on immune function in adult bronchial asthma in remission stage patients.Methods:One hundred and ten cases of adult bronchial asthma in remission stage patients in our hospital during July 2013 to April 2016 were chosen as research subject,treatment methods were reviewed and all patients were divided into control group(n =58)underwent normal western medicine treatment only,observation group(n =52)underwent Jinkuishenqiwan adjuvant therapy plus normal western medicine treatment.Before and after treatment,peripheral blood Th17/Treg cell ratio,serum Th1/Th2 cytokines and humoral immune indexes between two groups were compared.Results:Before treatment,there were no significant difference between two groups about peripheral blood Th17/Treg cell ratio,serum Th1/Th2 cytokines and humoral immune indexes (P ＞ 0.05).After treatment,Th17 cells and the ratio of Th1 7/Treg in observation group in peripheral blood were lower than those in control group,Treg cells was higher than that in control group;serum contents of IL-2,IFN-γwere higher than those in control group,IL-4,IL-5 were lower than those in control group;serum contents of humoral immunity indexes such as IgE、C3 were lower than that in control group(P ＜ 0.05).Conclusion:Jinkuishenqiwan adjuvant therapy can relieve the cellular immunity,humoral immune function in patients with optimization of adult bronchial asthma,has positive clinical significance.关键词
支气管哮喘缓解期/金匮肾气丸/免疫功能Key words
Bronchial asthma in remission stage/Jinkuishenqiwan/Immune function分类
医药卫生引用本文复制引用
张静,陶志国,许保海..金匮肾气丸辅助治疗对支气管哮喘缓解期患者免疫功能的影响[J].世界中医药,2017,12(7):1569-1572,4.基金项目
国家自然科学基金青年科学基金项目(31601078) （31601078）
