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磁小体膜蛋白Mms6功能与应用研究进展

马坤 赵宏鑫 李倩 王嘉榕 孙红宾

生物技术通报2017,Vol.33Issue(9):48-55,8.
生物技术通报2017,Vol.33Issue(9):48-55,8.DOI:10.13560/j.cnki.biotech.bull.1985.2017-0170

磁小体膜蛋白Mms6功能与应用研究进展

Research Progress on the Function and Application of Membrane Protein Mms6 of Magnetosome

马坤 1赵宏鑫 1李倩 2王嘉榕 1孙红宾1

作者信息

  • 1. 中国科学院强磁场科学中心,合肥 230031
  • 2. 中国科学技术大学生命科学院,合肥 230031
  • 折叠

摘要

Abstract

The magnetosome is a special biomineralized product formed by the invagination of the magnetotactic bacteria(MTB)inner membrane. Magnetosome is composed of membrane-enclosed magnetite crystals ordered into chains along the cell. Moreover,these magnetic nanocrystals are highly homogeneous in size and morphology. The magnetosome membrane protein has been demonstrated to play an important role in the formation of magnetosome with recruitment and redox of iron and regulation of the nucleation and growth of magnetic nanocrystals. This article reviews that the main function of protein in magnetosome membrane in the process of the formation of magnetic nanoparticles from the absorption of iron ions into mineralization. Especially,the article introduces the structure characteristics and functions of the magnetosome membrane special protein 6(Mms6). Furthermore,the article summarizes the application of Mms6,as a biomimic addictive in the new-type magnetic nanomaterials,and discusses its possible mechanism of molecular regulation during the process of the formation of magnetosome,for providing a better understanding of biomineralization.

关键词

磁小体/生物矿化/Mms6蛋白/仿生材料合成

Key words

magnetosome/biomineralization/mms6 protein/biomimeticsynthesis

引用本文复制引用

马坤,赵宏鑫,李倩,王嘉榕,孙红宾..磁小体膜蛋白Mms6功能与应用研究进展[J].生物技术通报,2017,33(9):48-55,8.

基金项目

国家自然科学基金项目(U1332142)(21372222) (U1332142)

生物技术通报

OA北大核心CSCDCSTPCD

1002-5464

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