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蜕膜巨噬细胞在母胎界面调控机制的研究进展

王楠 何亚萍 王健

生殖医学杂志2017,Vol.26Issue(9):946-950,5.
生殖医学杂志2017,Vol.26Issue(9):946-950,5.DOI:10.3969/j.issn.1004-3845.2017.09.018

蜕膜巨噬细胞在母胎界面调控机制的研究进展

Advances in regulation mechanism of decidual macrophages at maternal-fetal interface

王楠 1何亚萍 1王健1

作者信息

  • 1. 上海市计划生育科学研究所国家卫生计生委计划生育药具重点实验室,上海200032
  • 折叠

摘要

Abstract

The formation and maintenance of the immune state at the maternal fetal interface is the key to establishment and smooth progress of the pregnancy process.The decidual immune cells play an important regulatory role.In the decidual tissue of early pregnancy,macrophages (decidual macrophages,dMφ) are changed from M φ1 to Mφ2 phenotype.Decidual macrophages play anti-inflammatory and phagocytic effect,regulate the local immune function of the decidual,and participate in the regulation of embryo implantation and pregnancy maintenance process.

关键词

母胎界面/蜕膜巨噬细胞/免疫耐受

Key words

Maternal-fetal interface/Decidual macrophages/Immune tolerance

引用本文复制引用

王楠,何亚萍,王健..蜕膜巨噬细胞在母胎界面调控机制的研究进展[J].生殖医学杂志,2017,26(9):946-950,5.

基金项目

国家自然科学基金面上项目(81671459) (81671459)

生殖医学杂志

OACSTPCD

1004-3845

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