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柠条锦鸡儿不同极性部位抗氧化及抗须癣毛癣菌活性初筛

曾智 徐恒 白波 王洪伦 索有瑞

天然产物研究与开发2017,Vol.29Issue(8):1362-1367,6.
天然产物研究与开发2017,Vol.29Issue(8):1362-1367,6.DOI:10.16333/j.1001-6880.2017.8.018

柠条锦鸡儿不同极性部位抗氧化及抗须癣毛癣菌活性初筛

Preliminary Screening for Antioxidant and Anti-Trichophyton mentagrophyte Activities of Different Polarity Extracts from Caragana korshinskii Kom.

曾智 1徐恒 2白波 1王洪伦 2索有瑞1

作者信息

  • 1. 中国科学院西北高原生物研究所藏药重点实验室,西宁810008
  • 2. 中国科学院大学,北京100049
  • 折叠

摘要

Abstract

In this study,the flowers,leaves,bark and root of Caragana korshinskii Kom.were separately extracted by ethanol.And then all the extracts were further fractionated by petroleum ether (Pe) and ethyl acetate (Et) in sequence.Those extracts were applied to screen the anti-oxidant and anti-fungal activities.The anti-oxidant activity was carried out by scavenging radicals of DPPH,ABTS,hydroxyl radical (· OH) and superoxide anion (O2-).Inhibition zone was employed to evaluate the anti-fungal activity of those extracts.The results suggested that compared with vitamin C (Vc) the flowers and leaves of C.korshinskii showed good anti-oxidant activity of scavenging radical of DPPH and ABTS,especially for their Et fractions.However,all parts of the extracts showed weaker activity of scavenging · OH and O2-than Vc (p < 0.001).Screening for anti-fungal activity,the results showed that the Et fraction of flowers,leaves and bark are anti-fungal of Trichophyton mentagrophyte to some extent,especially the bark.Moreover,the inhibition ratio can be up to 50% when the concentration of the Et fraction of bark collected in autumn.Those consequences turned out that flowers and leaves of C.korshinskii can be a potential and exploitative resource.

关键词

柠条锦鸡儿/抗氧化/须癣毛癣菌/活性初筛

Key words

Caragana korshinskii Kom./antioxidant activity/Trichophyton mentagrophyte/screening activity

分类

医药卫生

引用本文复制引用

曾智,徐恒,白波,王洪伦,索有瑞..柠条锦鸡儿不同极性部位抗氧化及抗须癣毛癣菌活性初筛[J].天然产物研究与开发,2017,29(8):1362-1367,6.

基金项目

青海省科技厅星火计划(2015-NK-302) (2015-NK-302)

天然产物研究与开发

OA北大核心CSCDCSTPCD

1001-6880

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