慢性心力衰竭患者血浆TIMP-4、sES及FFA动态变化及预后判断OACSTPCD
Study on Dynamic Variation of Plasma Levels of TIMP-4, sES and FFA in Patients with Chronic Heart Failure and the Prognosis Judgment
目的 探讨慢性心力衰竭(CHF)患者血浆组织型金属蛋白酶抑制剂-4(TIMP-4)、可溶性E-选择素(sES)和游离脂肪酸(FFA)的动态变化以及判断预后的临床价值.方法 选择确诊CHF患者118例,根据心力衰竭严重程度分为:轻度组,共73例,心功能分级(NYHA)Ⅱ级;重度组,共45例,心功能分级(NHA)Ⅲ～Ⅳ级.于治疗的第1、3、6、12个月分别检测并比较两组患者血浆N末端脑钠肽原(NT-proBNP)、TIMP-4、sES及FFA水平的差…查看全部>>
Objective To explore the clinical value of the dynamic variation of plasma levels of the tissue inhibitor of metalloproteinase (TIMP)-4,soluble E selectin (sES) and free fatty acids (FFA) in patients with chronic heart failure (CHF) as well as the correlation of plasma levels of TIMP-4,sES and FFA to prognostic judgment.Methods A total of 118 patients with CHF were collected and divided into two groups according to the degree of CHF,which were mild group (73…查看全部>>
魏红随;王刚;刘兴芝
071400 河北省蠡县医院内四科073000 河北省第七人民医院心血管内科073000 河北省定州市第二医院内科
医药卫生
慢性心力衰竭组织型金属蛋白酶抑制剂-4可溶性E选择素游离脂肪酸
Chronic heart failure, Metalloproteinase (TIMP)-4, Soluble E selectin (sES)Free fatty acidsPrognosis
《心脑血管病防治》 2017 (4)
256-259,4
2015年度河北省医学科学研究重点课题计划(20150552)
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