中国医疗设备2017，Vol.32Issue(9)：23-28,52,7.DOI:10.3969/j.issn.1674-1633.2017.09.006
温控射频消融温度场仿真模型参数敏感性分析
Parametric Sensitivity Analysis of Simulation Model for Temperature-Controlled Radiofrequency Ablation Temperature Field
摘要
Abstract
Objective To study the sensitivity of the characteristic parameters in the temperature-controlled radiofrequency ablation (RFA) temperature field model and to analyze the significance of these parameters for the temperature distribution. Methods The finite element method was used to establish the temperature field simulation model. The variance contribution rate (SS％) and the main effect of the characteristic parameters on the size and the temperature of the ablation area were then discussed based on the variance analysis theory. Results The study showed that in the near field region, the SS％ of the electrical conductivity (Sigma) and the tissue equivalent resistance (R) were about 22％ in the early ablation session and about 47.5％ in the posterior ablation session. In the far field region, the SS％ of Sigma and R were about 26.9％ and 43％ respectively in the early and posterior ablation stage;with regard to ablation area size, the SS％ of Sigma and R were about 36％ and 46.5％ in the early and posterior ablation stage, respectively. According to the main effect analysis, Sigma and R were directly correlated with temperature, specific heat capacity and density were inversely-related to temperature, and the correlation between thermal conductivity and temperature varied with time and position. Conclusion During in the RFA thermal ablation, compared with the thermal conductivity, density, specific heat capacity and dielectric constant, electrical conductivity and tissue equivalent resistance have significant sensitivity.关键词
射频消融/温度场仿真/模型参数/敏感性分析Key words
radiofrequency ablation/temperature field simulation/model parameters/sensitivity analysis分类
医药卫生引用本文复制引用
王笑茹,高宏建,吴水才,白燕萍..温控射频消融温度场仿真模型参数敏感性分析[J].中国医疗设备,2017,32(9):23-28,52,7.基金项目
国家自然科学基金资助项目(71661167001) （71661167001）
北京市自然科学基金资助项目(7174279). （7174279）
