中国感染控制杂志2017，Vol.16Issue(9)：804-806,3.DOI:10.3969/j.issn.1671-9638.2017.09.003
新生儿监护病房无乳链球菌临床分布及耐药性分析
Clinical distribution and antimicrobial resistance of Streptococcus agalactiae in neonatal intensive care unit
摘要
Abstract
Objective To investigate the clinical distribution and antimicrobial resistance of Streptococcus agalactiae(S.agalactiae) in neonatal intensive care unit(NICU), and provide reference for antimicrobial use and intervention measures.Methods Specimens from neonates in the NICU of a hospital in 2010-2014 were collected, the department sources and antimicrobial susceptibility testing results of 62 strains of S.agalactiae isolated from children were analyzed.Results 62 strains of S.agalactiae were mainly distributed at full-term NICU, accounting for 64.52％;the main source of specimens was blood, accounting for 90.33％, followed, by cerebrospinal fluid (6.45％), sputum, and secretion(both were 1.61％).S.agalactiae had the highest resistance rate to tetracycline(79.03％);resistance rates to erythromycin and clindamycin were both 74.19％, resistance rate to levofloxacin was 40.32％, susceptibility rates to penicillin and ampicillin were both 100％.Conclusion S.agalactiae infection mainly occurred in neonates in full-term NICU, and has high resistance rate to multiple antimicrobial agents, penicillin and ampicillin can be used as the preferred antimicrobial agents for the treatment of S.agalactiae infection.关键词
新生儿/无乳链球菌/临床分布/耐药性Key words
neonate/Streptococcus agalactiae/clinical distribution/drug resistance分类
医药卫生引用本文复制引用
章晟,庄璐,李秋平,韦秀娟,宋婕,张玉佩,封志纯..新生儿监护病房无乳链球菌临床分布及耐药性分析[J].中国感染控制杂志,2017,16(9):804-806,3.基金项目
中国博士后科学基金项目(2013M542472) （2013M542472）
