中国感染控制杂志2017，Vol.16Issue(9)：829-832,4.DOI:10.3969/j.issn.1671-9638.2017.09.009
早产儿真菌血症临床特点
Clinical characteristics of fungemia in premature infants
常淑婷 1黄维清 1刘新晖 1李强 1马金霞 1杨志明 1高喜容1
作者信息
- 1. 湖南省儿童医院,湖南 长沙 410007
- 折叠
摘要
Abstract
Objective To realize the clinical characteristics of fungemia in premature infants.Methods Clinical characteristics of fungemia in premature infants in the intensive care unit of a children''s hospital between January 2011 and December 2015 were analyzed retrospectively, general condition of premature infants, laboratory-related indicators, and antimicrobial susceptibility testing results were compared.Results From January 2011 to December 2015, 42 premature infants with confirmed fungemia were treated in this hospital, 22 (52.38％) of whom were with fungemia caused by Candida albicans(C.albicans), 13 (30.95％) by Candida parapsilosis (C.parapsilosis), 3 by Candida krusei (C.krusei), and 4 by other fungi.Patients were grouped according to the main pathogens causing infection: C.parapsilosis group and C.albicans group.Maternal genitourinary tract infection rate and incidence of fungal meningitis in C.albicans group were both higher than C.parapsilosis group(27.27％ vs 7.69％, 27.27％ vs 0.00％ respectively), peripherally inserted central catheter (PICC) rate in C.albicans group was lower than that in C.parapsilosis group(22.73％ vs 69.23％), platelet count in C.parapsilosis group was lower than C.albicans group, differences were all statistically significant (all P<0.05).Conclusion The major fungi causing fungemia in premature infants were C.parapsilosis and C.albicans, maternal reproductive system infection during pregnancy can easily lead to candidemia, premature infants with candidemia are more vulnerable to developing fungal meningitis;PICC is more likely to lead to C.parapsilosis fungemia, and platelet decline is more obvious.关键词
婴儿,早产/真菌血症/白假丝酵母菌/近平滑假丝酵母菌Key words
infant/premature/fungemia/Candida albicans/Candida parapsilosis分类
医药卫生引用本文复制引用
常淑婷,黄维清,刘新晖,李强,马金霞,杨志明,高喜容..早产儿真菌血症临床特点[J].中国感染控制杂志,2017,16(9):829-832,4.
