中国实用口腔科杂志2017，Vol.10Issue(8)：484-487,4.DOI:10.19538/j.kq.2017.08.009
不同吸入氧浓度对颌面外科手术麻醉新生儿肺功能及炎症因子影响研究
Effects of different concentrations of oxygen inhalation on pulmonary function and inflammatory factors in pediatric patients with maxillofacial surgery
摘要
Abstract
Objective To investigate the effects of different concentrations of oxygen inhalation on pulmonary function and inflammatory factors in patients with maxillofacial surgery.Methods The 90 pediatric patients undergoing maxillofacial surgery in the Affiliated Stomatological Hospital of China Medical University from May 2015 to October 2016 were randomly divided into three groups,35％,50％,75％ FiO2 were inhaled.Preoperative,intraoperative and postoperative monitoring was performed on blood gas and lung function index;peripheral inflammatory factor changes were detected by ELISA.Results There was no significant difference in body weight,operation time,transfusion volume,blood loss or urine volume between the three groups (P ＞ 0.05).During mechanical ventilation,LA,pH and HCO3-levels were no significant difference among the three groups(P ＞ 0.05).Preoperative oxygen pressure is normal in the three groups,and oxygen partial pressure was statistically increased compared with preoperative group (P ＜ 0.05);postoperative oxygen partial pressure decreased,and compared with preoperative,the difference was statistically significant (P ＜ 0.05).The oxygen partial pressure of B group continued to rise,and the difference was statistically significant (P ＜ 0.05);the oxygen partial pressure of C group was increased in the operation,and the difference was statistically significant (P ＜ 0.05).In group A,the IL-1 beta was significantly decreased,and the IL-10 was increased,and compared with the preoperative phase there was significant difference (P ＜ 0.05).Conclusion Effects of inhalation of 35％ oxygen on pulmonary function and inflammatory factors are least significant in patients undergoing maxillofacial surgery.关键词
机械通气/氧浓度/肺损伤/炎症反应Key words
mechanical ventilation/oxygen concentration/lung injury/inflammatory reaction分类
医药卫生引用本文复制引用
崔海彬,张倩..不同吸入氧浓度对颌面外科手术麻醉新生儿肺功能及炎症因子影响研究[J].中国实用口腔科杂志,2017,10(8):484-487,4.基金项目
辽宁省科技攻关项目(2013225220) （2013225220）
