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microRNA在固有免疫中的作用研究进展

杨若聪 段飞鹏 曹佳红 田朋朋 闫智勇 李韶菁

中国药科大学学报2017,Vol.48Issue(4):396-406,11.
中国药科大学学报2017,Vol.48Issue(4):396-406,11.DOI:10.11665/j.issn.1000-5048.20170403

microRNA在固有免疫中的作用研究进展

Advances of microRNA activity in innate immunity

杨若聪 1段飞鹏 2曹佳红 3田朋朋 2闫智勇 1李韶菁2

作者信息

  • 1. 中国中医科学院中药研究所,北京100700
  • 2. 西南交通大学生命科学与工程学院,成都610031
  • 3. 北京中医药大学中药学院,北京100029
  • 折叠

摘要

Abstract

MicroRNA (miRNA),sharing the character of regulating the transcriptional level and expression level of mRNAs,is one kind of small non-coded RNAs.At present,innate immune has become one of the hot topics for researchers,and miRNAs as a sort of bioactive substance greatly take part in the whole regulation progress.In detailed,miRNAs can influence the immune state of immune cells during innate immune period and further regulate inflammatory conditions in whole body.By systematically summarizing miRNA function during innate immunity,this present review may provide a reference for peer researchers.

关键词

microRNA/固有免疫/炎症/进展

Key words

microRNA/innate immune/inflammation/advances

分类

生物科学

引用本文复制引用

杨若聪,段飞鹏,曹佳红,田朋朋,闫智勇,李韶菁..microRNA在固有免疫中的作用研究进展[J].中国药科大学学报,2017,48(4):396-406,11.

基金项目

国家“重大新药创制”科技重大专项资助项目(No.2012ZX09103-201-055) (No.2012ZX09103-201-055)

国家自然科学基金资助项目(No.81274133,No.81303261)This study was supported by the the Major Scientific and Technological Special Project for "Significant New Drugs Creation" (No.2012ZX09103-201-055) (No.81274133,No.81303261)

and the National Natural Science Foundation of China (No.81274133,No.81303261) (No.81274133,No.81303261)

中国药科大学学报

OA北大核心CSCDCSTPCD

1000-5048

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