中国药科大学学报2017，Vol.48Issue(4)：416-424,9.DOI:10.11665/j.issn.1000-5048.20170405
以热休克蛋白HSP70为靶点的药物研究进展
Advances of targeting heat shock protein 70 drugs
摘要
Abstract
Heat shock protein 70 (HSP70) family is one ofthe most conserved proteinin evolutionand plays critical,role in proteostasis.HSP70 is becoming an interesting target for multiple diseases such as cancer and Alzheimer's disease.There are many drugs targeted to HSP70 in preclinical study.In this review,the classification,the structure,the function of HSP70,and the drugs of the HSP70 family are reviewed.关键词
HSP70/结构/功能/靶点/激动剂/进展Key words
HSP70/function/inhibitors/agonists/advances分类
医药卫生引用本文复制引用
刘宗亮,张仁梅,孟庆国..以热休克蛋白HSP70为靶点的药物研究进展[J].中国药科大学学报,2017,48(4):416-424,9.基金项目
国家自然科学基金资助项目(No.81502983)This study was supported by the National Natural Science Foundation of China (No.81502983) （No.81502983）
