中国药理学通报2017，Vol.33Issue(10)：1350-1353,4.DOI:10.3969/j.issn.1001-1978.2017.10.005
长期使用伏立康唑引发的骨膜炎和鳞状细胞癌
Periostitis and squamous cellcarcinoma induced by long-term use of voriconazole
施丽红 1罗佳 1李慧兰 1朱苗苗 1张赞玲1
作者信息
- 1. 中南大学湘雅医院药学部,湖南 长沙 410008
- 折叠
摘要
Abstract
Voriconazole is a broad spectrum triazole antifungal agent, widely used in the prevention and treatment of invasive fungal diseases.Long-term use of voriconazole can induce periostitis and cutaneous squamous cell carcinoma, accounting for serious adverse effects on patients, which has been reported in increasing clinical cases.This review is to characterize the epidemiological and clinical manifestations of periostitis and squamous cell carcinoma induced by voriconazole, and to analyze the mechanisms of triggering periostitis and squamous cell carcinoma, so as to promote the rational use of voriconazole in clinics.关键词
伏立康唑/长期治疗/不良反应/骨膜炎/鳞状细胞癌/机制Key words
voriconazole/long-term treatment/adverse reaction/periostitis/squamous cell carcinoma/mechanism分类
医药卫生引用本文复制引用
施丽红,罗佳,李慧兰,朱苗苗,张赞玲..长期使用伏立康唑引发的骨膜炎和鳞状细胞癌[J].中国药理学通报,2017,33(10):1350-1353,4.
