中国药业2017，Vol.26Issue(17)：26-28,3.DOI:10.3969/j.issn.1006-4931.2017.17.008
非水电位滴定法测定阿伐斯汀原料的含量
Content Determination of Acrivastine by Non-Aqueous Potentiometric Titration
黄俊1
作者信息
- 1. 重庆市食品药品检验检测研究院,重庆 401121
- 折叠
摘要
Abstract
Objective To establish an accurate and convenient method for content determination of acrivastine. Methods The potentio-metric titration was performed with KEM AT610 potentiometric titrator and KEM C-173 electrode using 30 mL glacial acetic acid as solvent. Results The sudden change of titration end point was significant, the reproducibility was good ( RSD=0. 12％, n=6 ) , the linear range of acrivastine was 0. 012-0. 144 g ( r=1. 000 ) . Conclusion The non-aqueous potentiometric titration method is simple and rapid, and it can be used for the determination of acrivastine.关键词
非水电位滴定法/阿伐斯汀/含量测定Key words
non-aqueous potentiometric titration/acrivastine/content determination分类
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黄俊..非水电位滴定法测定阿伐斯汀原料的含量[J].中国药业,2017,26(17):26-28,3.
