摘要
Abstract
Objective To analyze the clinical effect and safety of intravenous thrombolysis with alteplase for treating acute ischemic stroke. Methods Totally 64 patients with acute ischemic stroke within 4. 5 h in our hospital in 2016 were selected and divided into 2 groups according to the different medication,32 cases in each group. The treatment group received intravenous thrombolysis with alteplase,while the control group was given aspirin. Results The total effective rate of the treatment group was 93. 75%,which was significantly higher than 81. 25% of the control group(P < 0. 05). After 6 h,24 h and 7 d of the treatment,the scores of NIHSS in the treatment group were (11. 8 ± 3. 1) points,(7. 5 ± 2. 7) points,(5. 6 ± 4. 5) points,which were significantly lower than (13. 5 ± 2. 9) points,(9. 5 ± 2. 1)points,(7. 8 ± 3. 6)points in the control group (P < 0. 05). There was no significant difference in adverse drug reactions between the two groups(P > 0. 05). Conclusion At the time of therapeutic time window within 4. 5 h,intravenous thromboly-sis with alteplase for treating acute ischemic stroke has good effect and safety,which is worthy of clinical promotion.关键词
阿替普酶/静脉溶栓/急性缺血性脑卒中/安全性/临床疗效Key words
alteplase/intravenous thrombolysis/acute ischemic stroke/safety/clinical effect分类
医药卫生
