中国药业2017，Vol.26Issue(18)：70-72,3.DOI:10.3969/j.issn.1006-4931.2017.18.026
醒脑静联合乙酰谷酰胺治疗急性重度一氧化碳中毒45例临床观察
Clinical Observation of Xingnaojing Combined with Acetylglutamide for Treating Acute Severe Carbon Monoxide Poisoning in 45 Cases
陆岩 1方建飞 1王芳 1罗晓燕 1李伟1
作者信息
- 1. 河北省开滦总医院,河北唐山 063000
- 折叠
摘要
Abstract
Objective To investigate the clinical effect of Xingnaojing combined with acetylglutamide in the treatment of acute severe carbon monoxide poisoning. Methods A total of 90 patients with acute severe carbon monoxide poisoning admitted to our hospital from January 2012 to January 2017 were selected and divided into the control group (n=45)and the observation group (n=45)according to random number table method. The two groups were treated with hyperbaric oxygen,nutrition nerve,mannitol dehydration to reduce intracranial pressure and improve circulation and other basic treatment,on this basis,the control group was treated with acetylglutamide, while the observation group was additionally treated with Xingnaojing on the basis of the control group. Results The total effective rate of the observation group was 93. 33%,which was significantly higher than 75. 56% of the control group (P < 0. 05). After treatment, the GCS score and serum SOD level were significantly increased in the two groups,and the observation group was increased more significantly (P < 0. 05). The incidence rate of delayed encephalopathy of the observation group was 4. 44%,which was significantly lower than 22. 22% of the control group (P < 0. 05). Conclusion Xingnaojing combined with acetylglutamide is effective in the treatment of patients with severe acute carbon monoxide poisoning,and it also can reduce the incidence of delayed encephalopathy,which is worthy of clinical promotion.关键词
醒脑静/乙酰谷酰胺/急性重度一氧化碳中毒/临床疗效Key words
Xingnaojing/acetylglutamide/severe acute carbon monoxide poisoning/clinical effect分类
医药卫生引用本文复制引用
陆岩,方建飞,王芳,罗晓燕,李伟..醒脑静联合乙酰谷酰胺治疗急性重度一氧化碳中毒45例临床观察[J].中国药业,2017,26(18):70-72,3.
