中国真菌学杂志2017，Vol.12Issue(4)：212-215,4.
以坏死性肉芽肿为表现的肺隐球菌病28例临床影像分析
Pulmonary cryptococcosis presenting as necrotizing granuloma:a clinicopathologic analysis of 28 cases
张丽妍 1张冬蕾 2谭晓明 1谢惠康3
作者信息
- 1. 上海交通大学医学院附属仁济医院南院呼吸科,上海201112
- 2. 上海交通大学医学院附属仁济医院南院胸外科,上海201112
- 3. 同济大学附属上海市肺科医院病理科,上海200433
- 折叠
摘要
Abstract
Objective To improve the understanding of pulmonary cryptococcosis (PC) presenting as necrotizing granuloma and to avoid the misdiagnosis through the analysis on clinical,pathological and radiological characteristics.Methods A retrospective review of the clinicopathologic and radiological records of 28 cases of PC presenting as necrotizing granuloma comfirmed by special stains.Results There were 14 males and 14 females,aging from 27 to 68 years (median,51 years).Twenty-seven cases were asymptomaic while only one had cough.The previous history was chronic disease or cancer in 5 cases.CT scan of all cases showed node mass and four of them had a cavity.All cases were observed as necrotizing granuloma microscopically.Cryptococcus neoformans were seen by grocott hexamine silver and PAS staining.Conclusions The majority of PC patients presenting as necrotizing granuloma had normal immune system.Imaging findings were generally mass or cavity.Naked eye specimens were similar to the cancer.It was hard to distinguish necrotizing granuloma from tuberculosis granuloma unless by special staining.关键词
坏死性肉芽肿/隐球菌病/肺Key words
necrotizing granuloma/cryptococcosis/pulmonary分类
医药卫生引用本文复制引用
张丽妍,张冬蕾,谭晓明,谢惠康..以坏死性肉芽肿为表现的肺隐球菌病28例临床影像分析[J].中国真菌学杂志,2017,12(4):212-215,4.
