中国卒中杂志2017，Vol.12Issue(9)：822-826,5.DOI:10.3969/j.issn.1673-5765.2017.09.012
急性缺血性卒中患者认知功能障碍影响因素分析
Analysis of Influencing Factors of Cognitive Impairment in Patients With Acute Ischemic Stroke
摘要
Abstract
Objective To evaluate the influencing factors of cognitive impairment after acute ischemic stroke. Methods The study included 3285 patients who were subjects from the Study on Oxidative Stress in Patients with Acute Ischemic Stroke. The cognitive function of patients were determined by mini-mental state examination (MMSE), and the influence factors of cognitive impairment in patients with acute ischemic stroke were evaluated in multiple logistic regression analysis. Results The prevalence of cognitive impairment after acute ischemic stroke was 26.46％ (n=869), and the difference between the groups in the aspect of patient's age, sex, place of residence, education, exercise, and National Institutes of Health Stroke Scale (NIHSS) score were statistically significant. Logistic regression analysis showed that the risk factors of cognitive impairment after acute ischemic stroke were hyperlipidemia [odds ratio (OR) 1.38, 95％ confidence interval (CI) 1.01-1.89, P=0.043), women (OR 1.30, 95％CI 1.04-1.63, P=0.020), high National Institutes of Health Stroke Scale (NIHSS) score (OR 1.26, 95％CI 1.24-1.30, P<0.001), living in rural areas (OR 1.25, 95％CI 1.02-1.53, P=0.026) and advanced age (OR 1.03, 95％CI 1.02-1.04, P<0.001). High education level (OR 0.77, 95％CI 0.63-0.92, P=0.015) and frequent exercise (OR 0.80, 95％CI 0.66-0.97, P=0.020) wereprotective factors. Conclusion We should comprehensively take into account the influencing factors of cognitive impairment in patients with acute ischemic stroke.关键词
急性缺血性卒中/认知功能障碍/影响因素Key words
Acute ischemic stroke/Cognitive impairment/Influencing factors引用本文复制引用
陈永明,吕薇,张建明,贾晓琳,孟霞..急性缺血性卒中患者认知功能障碍影响因素分析[J].中国卒中杂志,2017,12(9):822-826,5.基金项目
北京市属医院科研培育计划项目(PX2016052) （PX2016052）
