针灸临床杂志2017，Vol.33Issue(7)：9-12,4.
经皮穴位电刺激对老年胆囊切除术后认知功能及血清S100β蛋白的影响
Effect of TEAS on Cognitive Function and Serum S100 Beta Protein in Senile Patients after Cholecystectomy
摘要
Abstract
Objective:To explore the effect of transcutaneous electrical acupoint stimulation(TEAS) on cognitive function in elderly patients after cholecystectomy and its possible mechanism.Methods:70 patients graded I to III according to Amercian Society of Anesthesiologists(ASA) grading, were randomly divided into the observation group and the control group, with 35 cases in each group.The observation group was given TEAS(points used were GV20, PC6, ST36, and SP6), whereas the control group was given sham-TEAS(same points as the observation group), the intervention of both groups were 30mins/day from the first day before operation to the seventh day after operation.Mini-Mental state examination(MMSE) score was recorded before operation and on 3rd and 7th day after operation, the rates of postoperative cognitive dysfunction(POCD) were recorded on 3rd and 7th day after operation;ELISA method was used to detect serum S100 beta protein before operation and on 3rd and 7th day after operation.Results:Three days after operation, MMSE score of the observation group was significantly higher than that of the control group(P<0.05), POCD rate and the level of S100 beta protein in the observation group were significantly lower than those of the control group(P<0.05);seven days after operation, there was no significant difference of relative indicators between the two groups(P>0.05).关键词
胆囊切除术/老年/经皮穴位电刺激/简易精神状态评价量表/认知功能障碍/血清S100β蛋白Key words
Cholecystectomy/Senile/Transcutaneous electrical acupoint stimulation/Mini-Mental state examination/Cognitive dysfunction/Serum S100 beta protein分类
医药卫生引用本文复制引用
谭新华..经皮穴位电刺激对老年胆囊切除术后认知功能及血清S100β蛋白的影响[J].针灸临床杂志,2017,33(7):9-12,4.基金项目
国家中医药管理局建设项目,编号:LP0118041. （）
