摘要
Abstract
Objective To analyze the risk factors of extrauterine growth retardation (EUGR) in very low birth weight infants.Methods Total 276 newborns with gestational age ≤32 weeks and weight ＜1 500g delivered in Women's Hospital Zhejiang University School of Medicine from January 2015 to December 2016 were enrolled in the study,including 104 cases of EUGR and 172 non-EUGR cases.The general condition,growth data,nutritional information and complications were compared between two groups,and the risk factors of EUGR were analyzed.Results Compared with the non-EUGR group,the gestational age,birth weight,average weight gain,discharged weight were lower,and the starting time of feeding,the time of full enteral feeding,the duration of parenteral nutrition were significantly longer in the EUGR group (all P＜0.05).In the EUGR group,the rate of intrauterine growth retardation,the rate of gestational hypertension,hormone administration during pregnancy,premature rupture of membrane were significantly higher than that in the non-EUGR group (all P＜0.05).The incidences of respiratory distress syndrome,bronchopulmonary dysplasia,patent ductus arteriosus,anemia,chronic lung disease were significantly different between two groups (all P＜0.05).Multivariate logistic regression showed that gestational age,birth weight,maternal administration of hormones,intrauterine growth restriction,respiratory distress syndrome,and time of full enteral feeding are independent risk factors of extrauterine growth retardation (all P＜0.05).Conclusion Gestational age,birth weight and intrauterine growth restriction and others are the risk factors of extrauterine growth retardation.Strengthening maternal health care,preventing intrauterine growth retardation and early enteral nutrition may effectively reduce the incidence of extrauterine growth retardation in very low birth weight infants.关键词
极低出生体重儿/宫外生长迟缓/影响因素Key words
Very low birth weight infants/Extrauterine growth retardation/Related risk factors
