中医药信息2017，Vol.34Issue(5)：80-83,4.
糖尿病足2号方对气虚血瘀型脱疽患者血管内皮细胞功能变化的临床研究
No.2 Diabetic Foot Formula on the Function of Vascular Endothelial Cells in Gangrene Patients with Qi deficiency and Blood Stasis
吴珣 1丁毅 1康煜冬 1王伏声 1王雨 1董雨1
作者信息
- 1. 首都医科大学附属北京中医医院,北京 100010
- 折叠
摘要
Abstract
Objective:To study No.2 Diabetic Foot Formula on the function of vascular endothelial cells in gangrene patients with qi deficiency and blood stasis.Method:69 patients with arteriosclerosis obliterans(ASO) were randomly divided into the observation group (36 cases) and the control group (33 cases).The control group was treated with Xuesaitong,whereas the observation group was treated with the combination of Xuesaitong and No.2 Diabetic Foot Formula.Clinical efficacy,ankle brachial index(ABI),and vascular endothelial growth factor(VEGF) were observed after 30 days treatment in both groups.Results:The levels of ABI and VEGF in both groups were decreased after treatment,and the levels in the observation group were significantly lower than those in the control group (P<0.05,P<0.01).The efficiency of the observation group was 100.00%,whereas the control group was 90.91%,which showed the observation group was better than the control group (P<0.05).Conclusion:No.2 Diabetic Foot Formula can reduce ABI and down-regulate VEGF to improve clinical efficacy for ASO patients.关键词
脱疽/气虚血瘀/血管内皮细胞/糖尿病足2号方Key words
Gangrene/Qi deficiency and blood stasis/Vascular endothelial cells/No.2 Diabetic Foot Formula分类
医药卫生引用本文复制引用
吴珣,丁毅,康煜冬,王伏声,王雨,董雨..糖尿病足2号方对气虚血瘀型脱疽患者血管内皮细胞功能变化的临床研究[J].中医药信息,2017,34(5):80-83,4.
