重庆医学2017，Vol.46Issue(25)：3484-3485,3488,3.DOI:10.3969/j.issn.1671-8348.2017.25.009
血清肿瘤标志物谱及趋化因子蛋白在肺癌中的表达及预测价值研究
Study on expression of serum tumor markers spectrum and chemokine protein in lung cancer and its predictive value
摘要
Abstract
Objective To analyze the expression and predictive value of serum tumor markers spectrum and chemokine protein in lung cancer and predictive value.Methods One hundred and fifty patients with lung cancer were selected as the observation group and contemporaneous 150 individuals undergoing physical examination served the control group.The levels of ProGRP,CEA,SCC and Cyfra21-1 were measured by chemiluminescence microparticle immunoassay.The chemokine protein was determined by multiple immunofluorescent assay.Results The levels of CCL28,LIF,LIGHT and GRO in the observation group were significantly higher than those in the control group (P＜0.05).The levels of CCL28,LIF,LIGHT and GRO in the observation group were higher than those in the control group.The levels of CCL28,NAP-2 and MDC in the observation group were lower than those in the control group (P＜0.05).Conclusion The regular detection of serum tumor markers spectrum and chemokine protein can predict the treatment prognosis and evaluate the clinical curative effect.关键词
肺肿瘤/胃泌素释放肽/癌胚抗原Key words
lung neoplasms/gastrin-releasing peptide/carcinoembryonic antigen分类
医药卫生引用本文复制引用
张楠,李铁军,李鲲鹏,白川盟,周继梧,赵增仁..血清肿瘤标志物谱及趋化因子蛋白在肺癌中的表达及预测价值研究[J].重庆医学,2017,46(25):3484-3485,3488,3.基金项目
国家自然科学基金资助项目(81072034). （81072034）
