海南医学院学报2017，Vol.23Issue(16)：2196-2199,4.DOI:10.13210/j.cnki.jhmu.20170811.011
抗阻+有氧运动锻炼对糖尿病大血管病变患者胰岛素抵抗、斑块性质及脂代谢的影响
Effect of resistance combined with aerobic exercise on insulin resistance, plaque properties and lipid metabolism in patients with diabetic macroangiopathy
摘要
Abstract
Objective: To study the effect of resistance combined with aerobic exercise on insulin resistance, plaque properties and lipid metabolism in patients with diabetic macroangiopathy.Methods: Patients with type 2 diabetes mellitus complicated with macroangiopathy who were treated in Zigong Third People's Hospital were selected as the research subjects, patients were randomly divided into exercise group and control group who received resistance + aerobic exercise combined with hypoglycemic therapy and routine hypoglycemic therapy respectively.The indexes of insulin resistance, plaque property and lipid metabolism were detected before intervention and 16 wk after intervention.Results: Sixteen weeks after intervention, serum F-Ins, MCP-1, YKL-40, MMP9, CatK, Caspase-3, TG, LDL, Resistin, Leptin and Visfatin contents of both groups of patients were significantly lower than those before intervention (P<0.05), and serum F-Ins, MCP-1, YKL-40, MMP9, CatK, Caspase-3, TG, LDL, Resistin, Leptin and Visfatin contents of exercise group were significantly lower than those of control group (P<0.05).Conclusion: Resistance combined with aerobic exercise can improve the insulin resistance, lipid metabolism and stabilize the plaque properties in patients with diabetic macroangiopathy.关键词
2型糖尿病/动脉粥样硬化/胰岛素抵抗/斑块性质/脂代谢Key words
Type 2 diabetes mellitus/Atherosclerosis/Insulin resistance/Plaque property/Lipid metabolism分类
医药卫生引用本文复制引用
胡明英..抗阻+有氧运动锻炼对糖尿病大血管病变患者胰岛素抵抗、斑块性质及脂代谢的影响[J].海南医学院学报,2017,23(16):2196-2199,4.基金项目
自贡市科技局课题项目(20165236)This study was supported by Project of Zigong Science and Technology Bureau (20165236). （20165236）
