海南医学院学报2017，Vol.23Issue(16)：2278-2281,4.DOI:10.13210/j.cnki.jhmu.20170829.016
丹七软胶囊辅助治疗对急性出血性脑血管病患者血清炎性因子、凝血功能及血液流变学指标的影响
Effect of Dan seven soft capsule adjuvant therapy on serum inflammatory factors, coagulation function and blood rheology indexes in patients with acute hemorrhagic cerebrovascular disease
摘要
Abstract
Objective: To investigate the effect of Dan seven soft capsule on the treatment of acute hemorrhagic cerebrovascular disease and the influence of serum inflammatory factors, coagulation function and blood rheology indexes.Methods: A total of 112 patients with acute hemorrhagic cerebrovascular disease were divided into the control group (n=57) and observation group (n=55) according to the random data table: the patients in the control group received routine treatment combined with edaravone, and on the basis of the treatment of the control group, the observation group was treated with Dan seven soft capsule.The serum levels of inflammatory factors, coagulation function and blood rheology indexes were compared between the two groups before and after treatment.Results: Before treatment, there were no significant difference in the inflammatory factors (hs-CRP, TNF-α and IL-6), blood coagulation function (FIB, PT and APTT) and hemorheology (high cut whole blood viscosity, low cut whole blood viscosity and plasma viscosity) levels between the control group and observation group.Compared with the levels of the same group before treatment, two groups of hs-CRP, TNF-α, IL-6, FIB, high cut whole blood viscosity, low cut whole blood viscosity and plasma viscosity levels after treatment were significantly decreased (P<0.05), and levels in the observation group were significantly lower than those in the control group (P<0.05).Compared with the group before treatment, the levels of PT and APTT in the two groups were significantly increased (P<0.05), and the observation group was significantly higher than the control group (P<0.05).Conclusion: Dan seven soft capsule in the treatment of acute hemorrhagic cerebrovascular disease can effectively reduce the level of serum inflammatory factors, improve coagulation function and blood rheology index, and it has an important clinical value.关键词
急性出血性脑血管病/丹七软胶囊/炎性因子/凝血功能/血液流变学Key words
Acute hemorrhagic cerebrovascular disease:Dan seven soft capsule/Inflammatory factors/Coagulation function/Blood rheology分类
医药卫生引用本文复制引用
桂树华,胡玲玲,王挺刚,眭晨燕,殷晓菁,孔亮..丹七软胶囊辅助治疗对急性出血性脑血管病患者血清炎性因子、凝血功能及血液流变学指标的影响[J].海南医学院学报,2017,23(16):2278-2281,4.基金项目
江苏省卫生厅科研项目(P201512)This study is supported by Research Project of Health Department in Jiangsu Province (grant No.P201512). （P201512）
