老年医学与保健2017，Vol.23Issue(4)：330-332,3.
胸部CT扫描测定肺动脉与主动脉直径比值与老年COPD患者血清炎症因子的相关性研究
Correlation between PA∶ A Ratio Measured by Chest CT Scan and Serum Inflammatory Factors in Elderly Patients with COPD
摘要
Abstract
Objective To study thecorrelation between the ratio of pulmonary artery diameter to aortic diameter (PA∶ A) and serum inflammatory factors measured dynamically in elderly patients with chronic obstructive pulmonary disease (COPD).Methods 90 cases with acute exacerbation chronic obstructive pulmonary disease (AECOPD) were enrolled and divided,according to chest CT scan,into 1 groups:group A (n=45,PA∶ A≤1) and group B (n=45,PA∶ A＞1);echocardiography and pulmonary function test were made to cases in both groups and the levels of serum IL-6,IL-21 and TNF-α were detected;the clinical data of all the cases were recorded,including admission and discharge time,follow-up for 6 and 12 months,acute exacerbation time and the number of death within12 months after discharge.Results The acute exerbation times and the number of death within12 months after discharge in group B were more and bigger than those in group A;there existed a statistical difference in PA∶ A raito,PASP,FEV1％ and the levels of serum IL-6,IL-21 and TNF-α between the 2 groups (P＜0.05);PA∶ A ratio was in positive correlation to PASP and the levels of serum IL-6,IL-21 and TNF-α but in negative correlation to FEV1％ in both groups (P＜0.05).Conclusions There exists a certain correlation between PA∶A ratio measured by chest CT scan and the levels of serum IL-6,IL-21 and TNF-α.关键词
老年/慢性阻塞性肺疾病/胸部CT扫描/PA∶A比值Key words
elderly/chronic obstructive pulmonary disease (COPD)/chest CT scan/pulmonary artery diameter to aortic diameter (PA∶ A)引用本文复制引用
孙荣,张银,丁薇,周晓莉,许德凤,赵云峰..胸部CT扫描测定肺动脉与主动脉直径比值与老年COPD患者血清炎症因子的相关性研究[J].老年医学与保健,2017,23(4):330-332,3.基金项目
上海市浦东新区科委科技发展基金课题(PKJ2015-Y51) （PKJ2015-Y51）
