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干扰素调节因子在肿瘤发生中的研究进展

陈妍洁 吴昊 沈锡中

中国临床医学2017,Vol.24Issue(4):644-649,6.
中国临床医学2017,Vol.24Issue(4):644-649,6.DOI:10.12025/j.issn.1008-6358.2017.20160800

干扰素调节因子在肿瘤发生中的研究进展

Progress of the interferon regulatory factors in the development of tumor

陈妍洁 1吴昊 1沈锡中1

作者信息

  • 1. 复旦大学附属中山医院消化科,上海 200032
  • 折叠

摘要

Abstract

Interferon regulatory factors(IRFs),which have 10 members,belong to the transcription factor family,and are named because of the regulation of interferon expression.They play important roles in the immune regulation,cell differentiation,cell apoptosis,and cell cycle regulation.This article will review the functional characteristics and immune activity of the family members,especially in the role of cell differentiation and tumor development.

关键词

干扰素调节因子/细胞免疫/免疫调节

Key words

interferon regulatory factors/cellular immunity/immune regulation

分类

医药卫生

引用本文复制引用

陈妍洁,吴昊,沈锡中..干扰素调节因子在肿瘤发生中的研究进展[J].中国临床医学,2017,24(4):644-649,6.

基金项目

上海市青年科技英才扬帆计划(16YF1401500),复旦大学附属中山医院青年基金(2015ZSQN08).Supported by Project of Youth Science and Technology Excellence of Shanghai (16YF1401500) and Youth Found of Zhongshang Hospital,Fudan University (2015ZSQN08). (16YF1401500)

中国临床医学

OACSTPCD

1008-6358

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