中国临床医学2017,Vol.24Issue(4):644-649,6.DOI:10.12025/j.issn.1008-6358.2017.20160800
干扰素调节因子在肿瘤发生中的研究进展
Progress of the interferon regulatory factors in the development of tumor
摘要
Abstract
Interferon regulatory factors(IRFs),which have 10 members,belong to the transcription factor family,and are named because of the regulation of interferon expression.They play important roles in the immune regulation,cell differentiation,cell apoptosis,and cell cycle regulation.This article will review the functional characteristics and immune activity of the family members,especially in the role of cell differentiation and tumor development.关键词
干扰素调节因子/细胞免疫/免疫调节Key words
interferon regulatory factors/cellular immunity/immune regulation分类
医药卫生引用本文复制引用
陈妍洁,吴昊,沈锡中..干扰素调节因子在肿瘤发生中的研究进展[J].中国临床医学,2017,24(4):644-649,6.基金项目
上海市青年科技英才扬帆计划(16YF1401500),复旦大学附属中山医院青年基金(2015ZSQN08).Supported by Project of Youth Science and Technology Excellence of Shanghai (16YF1401500) and Youth Found of Zhongshang Hospital,Fudan University (2015ZSQN08). (16YF1401500)