中国输血杂志2017，Vol.30Issue(7)：711-713,3.DOI:10.13303/j.cjbt.issn.1004-549x.2017.07.020
肝移植围手术期输血的综合评估
A comprehensive assessment of perioperative blood transfusion in liver transplantation
摘要
Abstract
Objective To evaluate the perioperative blood loss and blood transfusion in liver transplantation patients.Methods Retrospectively selected and classified 119 patients with liver transplantation medical recordsaccording to the clinical diagnosis of age,gender.Analyzed (disease)patients' blood coagulation index 24 h before surgery,intraoperative and postoperative perioperative bleeding,and blood red blood cell suspension,frozen plasma,cold precipitation,coagulation factor injection lossplateletpheresis.Results There were no significant differences in the amount of blood loss and the amount of blood preparations duringthe perioperative period of liver transplantation according to the age and sex of patients (P＞0.05);According to the clinical diagnosis of different groups,the diagnostic group (primary liver cancer group,hepatitis B cirrhosis group and severe hepatitis group) patients with a single platelet transfusion dosewas similar (P＞0.05)withsuspended red blood cells (U) at 8.4+11.9,16.2+15.7,18.1+13.5,frozen plasma (U) at 8.2+7.1,18.1+15.6 and 18.2+ 17.9 respectively andcold precipitation (U) at 9.5+ 8.2,17.1 + 16.318.5 + 16.4 (P＜ 0.05);The diagnosis group surgery before and after immediate PT (s) were 15.6+3.8,24.6+4.1,APTT (s) were 44.3+5.8,84.9+9.2,TT (s) were 20.4 +4.5,40.1+6.2,and Fib(s) were 2.6+0.8 and 1.3+0.9 (P＜0.05);however,there was no significant difference in the 24 h PT,APTT,TT and Fib between the two groups after diagnosis (P＞0.05).Conclusion Ascientific,safe and reasonable selection of perioperative blood preparation for clinical diagnosis for different liver transplantation patients is critical to the success rate and prognosis of liver transplantation;the evaluation of coagulation indexes at each interval can help guiding the blood transfusion during liver transplantation.关键词
输血/肝移植/围手术期/出血量/血液制剂/凝血指标Key words
blood transfusion/liver transplantation/perioperative period/bleeding volume/blood preparation/coagulation index分类
医药卫生引用本文复制引用
陈波,刘银,刘业,林艳,周晔,唐晓峰..肝移植围手术期输血的综合评估[J].中国输血杂志,2017,30(7):711-713,3.基金项目
上海市卫生和计划生育委员会科研课题(2014215),上海市公共卫生重点学科建设项目(15GWZK0501) （2014215）
