中国体外循环杂志2017，Vol.15Issue(3)：129-132,4.DOI:10.13498/j.cnki.chin.j.ecc.2017.03.01
五种心脏停搏液对未成熟心肌保护效果分析
The protective effects of five kinds of cardioplegia on immature myocardium during cardiopulmonary bypass
摘要
Abstract
Objective To analyze the protective effects of five kinds of cardioplegia on immature myocardium during cardiopulmonary bypass.Methods 180 cases of non-cyanotic congenital heart disease were divided randomly into 5 groups: group HTK,group St.Thomas,group 4:1 cold self-blood cardioplegia,group 1:1 cold self-blood cardioplegia,group 1:4 cold self-blood cardioplegia.Compare levels of cTnI and CKMB of 1 hour before operation,6 hours,12 hours and 48 hours after operation,as well as LVEF 1 h and 6 h before operation and after operation.Results There were no significant differences in cTnI and CKMB between 1 h before and 48 h after operation (P>0.05).There were no significant differences in LVEF between preoperation and 6 hours after operation (P>0.05).Levels of cTnI and CKMB in group HTK and group 1:4 cold self-blood cardioplegia were lower than other groups in 6 and 12 hours after operation(P<0.05);LVEF of group HTK and group 1:4 cold self-blood cardioplegia were higher than the other three groups in 1 hour after operation (P<0.05).Conclusion The HTK and cold self-blood cardioplegia with ratio 1:4 had better immature myocardial profective effects.关键词
先天性心脏病/自体血心脏停搏液/左室射血分数/心肌酶Key words
Congenictal heart disease/Self-blood cardioplegia/LVEF/Myocardial enzyme引用本文复制引用
孟保英,吴文智,丁以群,张青,潘晓兰,王元祥,彭乐..五种心脏停搏液对未成熟心肌保护效果分析[J].中国体外循环杂志,2017,15(3):129-132,4.基金项目
深圳市科技计划资助(JCYJ20150403100317074) （JCYJ20150403100317074）
