中国循证儿科杂志2017，Vol.12Issue(4)：273-277,5.DOI:10.3969/j.issn.1673-5501.2017.04.007
基于婴儿期日龄分期的新生儿后期新概念
Post-newborn period: a new concept of age period in early life after birth
摘要
Abstract
ObjectiveThe early life after birth, is very important to growth/development of children and health/disease of adult.However, the age boundary is inconsistent among pediatrician nowadays.The aim of the present study was to investigate the mortalities and causes of death of the neonatal period, post-newborn period(28 days after birth~100 days) and modified infant period(100 days after birth~1 year)for the new concept in early life after birth with post-newborn period.MethodsWe reviewed retrospectively the dead children of fourteen hospitals in west China from 2004 to 2013 and investigated the mortalities and causes of death of the neonatal period, post-newborn period and modified infant period.ResultsDuring 2004-2013, 155 463 infants aged 0 to 1 year were admitted to the hospitals, and 959 died.The total infant mortality was 6.16%.Significant differences were found in the mortality among the three periods (10.1% vs 6.9% vs 2.6%, P<0.001).Three main causes of death were different among three period: they were neonatal respiratory distress syndrome, neonatal asphyxia and congenital heart disease (CHD) in the neonatal period, pneumonia, CHD and premature-associated disease (PAD) in the post-newborn period, and pneumonia, CHD and accidental injuries in the modified infant period.Otherwise, four major diseases simultaneously appearing during the three periods(PAD, pneumonia, sudden infant death syndrome and CHD) showed inverse "U" shape changes from the neonatal period to the modified infant period, and the highest mortality occurred in the post-newborn period (P<0.001).ConclusionWithout gestational age and feeding mode being corrected as confounding factors, the mortality and etiology of post-newborn period have particularity, and which may mean special clinical values.In the future, more studies are needed to clarify the new-built concept and interpret its importance.关键词
新生儿期/新生儿后期/改良婴儿期/早产相关性疾病/先天性心脏病Key words
Neonatal period/Post-newborn period/Modified infant period/Premature-associated disease/Congenital heart disease引用本文复制引用
基于婴儿期日龄分期的新生儿后期新概念多中心协作组..基于婴儿期日龄分期的新生儿后期新概念[J].中国循证儿科杂志,2017,12(4):273-277,5.基金项目
重庆市科委精准医学重点专项基金:cstc2016shms-ztzx13001 （）
重庆市科委社会民生专项基金:cstc2015shmszx1201114 （）
