中国现代中药2017，Vol.19Issue(7)：944-955,12.DOI:10.13313/j.issn.1673-4890.2017.7.009
中药药对“都梁丸”化学成分的研究
Chemical Constituents from Couplet Medicine of "Duliang" Pill
摘要
Abstract
Objective:To study the chemical constituents of the couplet medicine of " Duliang" Pill.Methods:Repeated column chromatography on silica gel and HPLC were applied to the separation of compounds and their structures were determined by spectroscopic data analyses of MS and NMR.Results:Forty-one compounds were obtained and identified as 5-hydroxymethylfurfural (1),vanillin (2),ferulic acid (3),coniferyl aldehyde (4),xanthotoxin (5),bergaptol (6),falcarindiol (7),senkyunolide H (8),senkyunolide Ⅰ (9),senkyunolide D (10),4-hydroxy-3-butyl-phthalide (11),senkyunolide A (12),Z-ligustilide (13),3-butylidenephthalide (14),neocnidilide (15),levistolide A (16),β-sitosterol (17),isopimpinellin (18),dibutyl-O-phthalate (19),diisobutyl phthalate (20),chuanxiongdiolide R1 (21),atractylenolactam (22),bergapten (23),psoralen (24),isooxypeucedanin (25),phellopterin (26),heraclenol (27),pabularinone (28),anhydrobyakangelicin (29),imperatorin (30),isoimperatorin (31),alloisoimperatorin (32),oxypeucedanin hydrate (33),byakangelicin (34),(-)-marmesinin] (35),(2'S,3'R)-3'-hydroxymarmesinin (36),sec-O-β-D-gluco-pyranosylbyakangelicin (37),tert-O-β-D-glucopyranosylbyakangelicin (38),(2'R,3'S)-3'-hydroxynodakenin (39),xanthotoxol-8-O-β-D-glucopyranoside (40),and adenosine (41),respectively.Conclusion:Originally,coumarins and coumarin glycosides were from Angelicae Dahuricae Radix,and phthalides were from Chuanxiong Rhizoma.关键词
都梁丸/药对/白芷/川芎/化学成分Key words
The couplet medicine/Duliang Pill/Angelicae Dahuricae Radix/Chuanxiong Rhizoma/chemical constituents引用本文复制引用
韦玮,王力,梁丽,王逾珍,海丽娜,杨秀伟..中药药对“都梁丸”化学成分的研究[J].中国现代中药,2017,19(7):944-955,12.基金项目
国家自然科学基金项目(81473321) （81473321）
