国际神经病学神经外科学杂志2017，Vol.44Issue(4)：370-374,5.DOI:10.16636/j.cnki.jinn.2017.04.006
α-内收蛋白基因rs4963多态性与脑出血的关系
Association between polymorphism of rs4963 in the α-adducin gene and cerebral hemorrhage
摘要
Abstract
Objective To investigate the association between polymorphism of rs4963 in the α-adducm gene and cerebral nemorrnage.Methods A total of 238 patients with cerebral hemorrhage and 240 healthy controls were collected in Gansu,China.Blood genomic DNA extraction kit was used to evaluate the polymorphism of rs4963 in the oα-adducin gene,and the genotype and allele frequencies of rs4963 polymorphism were compared between the cerebral hemorrhage group and the control group.Results There were no significant differences in the genotype and allele frequencies between the cerebral hemorrhage group and the control group (P ＞ 0.05),even after the two groups were stratified by sex (P ＞ 0.05).Conclusions The polymorphism of rs4963 in the α-adducin gene is not associated with cerebral hemorrhage.关键词
脑出血/α-内收蛋白基因/甘肃地区Key words
cerebral hemorrhage/α-adducin gene/Gansu province引用本文复制引用
司江华,彭小兰,范红燕,严雯,谢守嫔,范彩霞..α-内收蛋白基因rs4963多态性与脑出血的关系[J].国际神经病学神经外科学杂志,2017,44(4):370-374,5.基金项目
兰州市卫生科技发展计划项目(LZWSKY2014-2-01) （LZWSKY2014-2-01）
