解放军医药杂志2017，Vol.29Issue(8)：48-50,3.DOI:10.3969/j.issn.2095-140X.2017.08.013
低蛋白饮食对糖尿病肾病治疗效果的评价研究
Effect of Low Protein Diet in Treatment of Patients with Diabetic Nephropathy
摘要
Abstract
Objective To evaluate effect of low protein diet in treatment of patients with diabetic nephropathy.Methods A total of 64 patients with diabetic nephropathy during March 2015 and January 2017 were randomly divided into research group and control group (n =32 for each group).All patients received regular diet guidance,and then research group was given a low-protein diet for 3 months.Body mass index (BMI),mean arterial pressure (MAP),hemoglobin (Hb),albumin (ALB),blood urea nitrogen (BUN),creatinine (Cr),uric acid,glomerular filtration rate (GFR),24 h urinary albumin and glycated hemoglobin (HbA1c),fasting plasma glucose (FPG),2 h postprandial blood glucose (2 h PG),serum triglyceride (TG) and serum total cholesterol (TC) levels were observed and compared before and after treatment in two groups.Results BMI,MAP,Hb,ALB,BUN,Cr,uric acid,GFR,24 h urinary albumin,HbA1 c,FPG,2 h PG,TG and TC in research group were superior to those before treatment and in control group (P ＜ 0.05).Conclusion High quality low-protein diet can improve GFR,alleviate glomerular sclerosis,improve serum ALB level and delay renal function injury of patients with diabetic nephropathy.关键词
糖尿病肾病/膳食,限制蛋白质/急性肾损伤Key words
Diabetic nephropathies/Diet, protein-restricted/Acute kidney injury分类
医药卫生引用本文复制引用
滑丽美,邱建宏,曹婧然..低蛋白饮食对糖尿病肾病治疗效果的评价研究[J].解放军医药杂志,2017,29(8):48-50,3.基金项目
河北省卫计委重点科技研究计划(20150387) （20150387）
