河北医学2017，Vol.23Issue(9)：1409-1412,4.DOI:10.3969/j.issn.1006-6233.2017.09.001
二氧化碳气腹对妇科子宫肌瘤腹腔镜手术患者术后早期认知功能的影响
Effect of CO2 Pneumoperitoneum on Early Cognitive Function in Patients with Gynecological Uterine Leiomyoma after Laparoscopic Surgery
摘要
Abstract
Objective:To investigate the effect of CO2 pneumoperitoneum at different pressures on early postoperative cognitive function in patients undergoing laparoscopic surgery for uterine fibroids. Methods:99 patients with uterine leiomyoma were enrolled from January 2015 to December 2015 were randomly divided into three groups. Group L was given low-pressure CO2 pneumoperitoneum. The patients of group M were given an intermediate pressure level of CO2 pneumoperitoneum. The patients of group H were given high pressure level of CO2 pneumoperitoneum. The three groups of patients with clinical observation, neurochemical markers and cognitive function were compared. Results:T2 and T3 PaCO2 levels and T1, T2 and T3 COR of group H were significantly higher than those in group L and group M;T2 and T3 PaCO2 levels and T1, T2 and T3 COR of group M were significantly higher than those in group L;T5 PaO2 level in patients with group H and group M was significantly lower than that in group L;T2, T3 and T4 NE the level was significantly higher than that of group L, T2, T1;T3 and T4 PGE2 were significantly higher than those in group L; group H of T1 patients with T2 NSE were significantly higher than those in group L and group M. S100β levels significantly higher than that in group L;T1 and T2 NSE of group M were significantly higher than those in group L, there was significant difference ( P<0.05) . Conclusion:Different air pressure pneumoperitoneum has little effect on the early cognitive function of patients with uterine leiomyoma after laparoscopic surgery, but low pressure CO2 pneumoperitoneum can relieve the body stress and reduce the release of neurochemical markers.关键词
二氧化碳/子宫肌瘤/腹腔镜手术/认知功能Key words
CO2/Uterine fibroids/Laparoscopic surgery/Cognitive function引用本文复制引用
马玉林,鲁信星,龚勇娟,石磊..二氧化碳气腹对妇科子宫肌瘤腹腔镜手术患者术后早期认知功能的影响[J].河北医学,2017,23(9):1409-1412,4.基金项目
陕西省卫生厅科研基金项目,(编号:2014JM4027) （编号:2014JM4027）
