河北医学2017，Vol.23Issue(9)：1498-1502,5.DOI:10.3969/j.issn.1006-6233.2017.09.027
动静脉联合溶栓与机械取栓治疗急性脑梗死的临床疗效及对患者预后的影响
Clinical Efficacy of Intravenous Thrombolysis combined with Mechanical Thrombectomy for Acute Cerebral Infarction and its Effect on Prognosis
摘要
Abstract
Objective: To investigate the clinical efficacy of intravenous thrombolysis combined with mechanical thrombectomy for acute cerebral infarction and its effect on prognosis. Method:96 patients with a-cute cerebral infarction in our hospital were selected and divided into Intravenous thrombolysis group and Thrombectomy group. There were 12 cases in the mechanical thrombectomy group, and the other in the intra-venous thrombolysis group, including thrombolysis in 22 cases, intravenous thrombolysis in 46 cases, and in-travenous thrombolysis in patients with arteriovenous shunt in 16 cases. The clinical efficacy and NIHSS score of the two groups were compared. Results: The total effective rate was 83.33％,higher than Bridging group (62.50％), artery group (54.55％) and the venous group (39.13％), the difference was statistically signifi-cant ( P<0.05);After treatment, the NIHSS scores of the four groups were decreased;and arterial thromboly-sis group and intravenous thrombolysis group and arteriovenous thrombolysis bridging group, thrombectomy group total vascular recanalization rate, lower NIHSS score, the difference has statistical significance ( P<0. 05);The incidence of intracranial hemorrhage occurred in 4 cases of arterial thrombolysis group (18.18％), Venous group of 8 cases ( 17. 39％) , Arteriovenous bridging group of 2 case ( 12. 5％) , The thrombectomy group 2 case (16.67％),there was no significant difference (P>0.05). Conclusion:The use of thrombectomy and thrombolysis method has certain therapeutic effect on acute cerebral infarction, but mechanical thrombec-tomy can effectively improve the recanalization rate, NIHSS score and clinical curative effect, promote the re-covery of physiological function of the patients.关键词
急性脑梗死/动脉溶栓/静脉溶栓/动静脉桥接溶栓/机械取栓Key words
Acute cerebral infarction/Arterial thrombolysis/Intravenous thrombolysis/Intrave-nous thrombolysis/Mechanical thrombectomy引用本文复制引用
肖文,蒲晓龙,柏杖勇,冯建新..动静脉联合溶栓与机械取栓治疗急性脑梗死的临床疗效及对患者预后的影响[J].河北医学,2017,23(9):1498-1502,5.基金项目
陕西省科技计划项目,(编号:2012K15-02-10) （编号:2012K15-02-10）
