湖南中医药大学学报2017，Vol.37Issue(9)：1008-1012,5.DOI:10.3969/j.issn.1674-070X.2017.09.022
温针灸联合非甾体类消炎药治疗膝骨关节炎的临床研究
Clinical Effect of Fire-needle Moxibustion Combined with NSAIDs on Knee Osteoarthritis
摘要
Abstract
Objective To observe the curative effect of adjunctive treatment of fire-needle moxibustion and non-steroidal anti-inflammatory drugs (NSAIDs) for knee osteoarthritis. Methods 80 patients of knee osteoarthritis (KOA) were random-ly divided into the control group and treatment group, 40 cases in each group. The control group was administrated with NSAIDs. The treatment group was given with an adjunctive treatment of fire-needle moxibustion and NSAIDs, 10 d for one course. Western Ontario and McMaster University Osteoarthritis Index (WOMAC) was determined before treatment and 1 day, 3 months, 6 months, and 12 months after treatment to evaluate the clinical effect. Results The scale of WOMAC in treat-ment group were significantly lower than those in control group (P<0.05), and the global scale of WOMAC maintained lower than control group until 12 months after treatment (P<0.05). The total effective rate of treatment group was higher than the control group during 1 day, 3 months, 6 months, and 12 months after treatment (P<0.05). tUntil 6 months postoperatively, the recovery and markedly-effective rate was significantly higher in the observation group compared with that in the control group (P<0.05). Further age stratified analysis showed that the differences between the observation group and control group among 60 years populations has gradually diminished, while in the patients <60 years old the global scale of WOMAC in the observa-tion group maintained lower than the observation group until 12 months after treatment (P<0.05). Conclusion The adjunctive treatment of fire-needle moxibustion and NSAIDs is effective for KOA, especially in the populations <60 years old, which is worthy of clinical popularization.关键词
膝骨关节炎/温针灸/非甾体类消炎药/骨关节炎指数Key words
knee osteoarthritis/fire-needle moxibustion/non-steroidal anti-inflammatory drugs/osteoarthritis index分类
医药卫生引用本文复制引用
沈金明,封蕾,陈杰,吴煜,于建农..温针灸联合非甾体类消炎药治疗膝骨关节炎的临床研究[J].湖南中医药大学学报,2017,37(9):1008-1012,5.基金项目
浙江省中医药科技计划(2017ZQ013) （2017ZQ013）
浙江省医药卫生科技项目 (2017KY501,2017KY078) （2017KY501,2017KY078）
浙江省自然科学基金(LY17H040005). （LY17H040005）
