国际眼科杂志2017，Vol.17Issue(10)：1852-1855,4.DOI:10.3980/j.issn.1672-5123.2017.10.12
长链非编码RNA在糖尿病视网膜病变中的作用
Role of long non - coding RNA in the pathogenesis of diabetic retinopathy
摘要
Abstract
Long non-coding RNA ( LncRNA) is a class of transcript (>200 nucleotides) that do not encode proteins. It plays an important role in epigenetic regulation and gene expression at transcriptional or post transcriptional level. The abnormal expression of LncRNA may lead to various pathological processes. Diabetic retinopathy ( DR ) is a multifactorial disease. Recent studies have shown that many specific expressions of LncRNAs are closely related to the genesis of DR. In this review, we summarized the recent advances in the function of LncRNA, the regulatory mechanisms of LncRNA involved in the development of DR, and the related therapies.关键词
长链非编码RNA/糖尿病视网膜病变/基因调控Key words
long non-coding RNA/diabetic retinopathy/gene regulation引用本文复制引用
岳秀娟,苏胜,刘平..长链非编码RNA在糖尿病视网膜病变中的作用[J].国际眼科杂志,2017,17(10):1852-1855,4.基金项目
国家自然科学基金资助项目( No. 81470618 ) （ No. 81470618 ）
黑龙江省自然科学基金资助项目( No. H2016038 ) （ No. H2016038 ）
黑龙江省博士后科研启动金资助(No. LBH-Q15102)National Natural Science Foundation of China (No. 81470618) （No. LBH-Q15102）
Natural Science Foundation of Heilongjiang Province ( No. H2016038 ) （ No. H2016038 ）
Heilongjiang Postdoctoral Scientific Research Developmental Fund (No. LBH-Q15102) （No. LBH-Q15102）
